Slouching Towards Oblivion

Showing posts with label cognitive dissonance. Show all posts
Showing posts with label cognitive dissonance. Show all posts

Wednesday, September 15, 2021

A Step Forward

Weirdly ironic - or maybe just a case of "Even a blind hog roots up an acorn now and again".

So Trump - the supposed champion darling of the All-Government-Is-Bad-Government crowd - throws a shit ton of money at the vaccine project, and we get some pretty fuckin' great results in a pretty fuckin' big hurry.

I wonder if they're feeling at all conflicted about heaping credit on a government-led success, and if that internal conflict has anything to do with the concerted efforts to shit-talk the vaccines.


Moderna's COVID-19 vaccine (mRNA-1273) is one of the handfuls that has received the WHO's approval so far. The vaccine is rooted in the company's pioneering mRNA (messenger RNA) platform. On Thursday, the US-based biotechnology firm announced promising pre-clinical data and stated that they have managed to successfully put together a single shot against three respiratory diseases—COVID-19, respiratory syncytial virus (RSV), and the flu.

In a social media post, Moderna said that it was able to combine 6 different mRNAs—one strain of COVID-19 and RSV each, and four strains of flu. Also, in another statement, the vaccine maker disclosed that it is developing a new vaccine that will be a combination of a COVID-19 vaccine booster shot and a flu shot. It also reported that candidates for a crucial cancer vaccine trial have been fully recruited.

"Today we are announcing the first step in our novel respiratory vaccine program with the development of a single-dose vaccine that combines a booster against COVID-19 and a booster against flu. We are making progress on enrolling patients in our rare disease programs, and we are fully enrolled in our personalized cancer vaccine trial," said Stéphane Bancel, Chief Executive Officer, Moderna, in the statement.

There's more, but you get the picture - when we get together and (more or less) all pull in the same direction, something good can happen that helps everybody.

And maybe that's the problem - the "conservatives" are so conditioned to expect nothing but bad news about government - in what should be seen as an obvious attempt to keep us all at each other's throats - that they just naturally assume any common good coming from anywhere is automatically suspect and must be something nefarious on the part of the global cabal or whatever bullshit DumFux News has piped into their brains lately.


And then this from Scientific American, because of course we have to run down every stoopid fucking crackpot notion whenever the rubes get whipped into a rich creamy lather again.

COVID Vaccines Show No Signs of Harming Fertility or Sexual Function

The novel coronavirus, in contrast, can disrupt both things in unvaccinated men and women


Rumors and myths about COVID-19 vaccine effects on all aspects of reproduction and sexual functioning have spread like a Delta variant of viral misinformation across social media platforms, where people swap rumors of erectile dysfunction and fertility disruptions following vaccination. Yet studies so far have not linked the vaccines with problems related to pregnancy, menstrual cycles, erectile performance or sperm quality. The evidence does show that COVID-19 can involve problems in all of these areas.

Health officials have tried to ease concerns by explaining that data from clinical trials and hundreds of millions of vaccinations support the safety of the shots. Scientific American spoke with four experts in reproductive and sexual biology about pervasive myths, the evidence against them and the real damage to health caused by COVID-19. Below is a series of conclusions that can be drawn from studies of vaccinated people and those who have had the disease.

Vaccination is not associated with adverse effects in pregnancy. COVID-19 is the real threat.

The U.S. Centers for Disease Control and Prevention updated its recommendations in early August, strengthening its advice that people who are pregnant or breastfeeding should be vaccinated against COVID-19.

The U.K.’s Medicines and Healthcare Products Regulatory Agency (MHRA) found this month that “there is no pattern ... to suggest that any of the COVID-19 vaccines used in the UK increase the risk of congenital anomalies or birth complications. Pregnant women have reported similar suspected reactions to the vaccines as people who are not pregnant.”

If infected with the virus, pregnant people are at highly increased risk for severe disease and complications from COVID-19, compared with their same-age counterparts, says Tara Shirazian, an associate professor and a gynecologist at NYU Langone Health.

The immune system effects of pregnancy itself make an infection about five times more likely, says Jane Frederick, a reproductive endocrinology and fertility specialist and medical director of HRC Fertility in California. “You get infected more quickly, and pregnant women can go downhill fast,” she adds.

People should take the opportunity to get vaccinated before conceiving, but the vaccine is safe across all three trimesters of pregnancy, says Mary Rosser, director of integrated women’s health at the Department of Obstetrics & Gynecology at Columbia University Irving Medical Center. In early August, 22 medical groups released a joint statement saying that “the best way for pregnant individuals to protect themselves against the potential harm from COVID-19 infection is to be vaccinated.”

The vaccines show no fertility effects, including among people using assisted reproductive techniques.

One origin of fertility falsehoods about the vaccines may be a letter co-written by a former Pfizer researcher and sent to the European Medicines Agency (EMA) in December 2020. The two authors asked that all vaccine studies be suspended. They claimed that vaccine-induced antibodies against a protein that SARS-CoV-2 uses to enter human cells might also attack another human protein needed for embryo implantation. SARS-CoV-2 is the virus that causes COVID.

A study published in June 2021 compared the success of transferring embryos to women who carried antibodies to SARS-CoV-2 after vaccination or infection to success rates among those without antibodies. The presence of antibodies did not appear to affect such rates during 171 transfer attempts.

In a New York Times essay, a pair of immunologists described their work showing that the sequences of amino acids that make up the implantation-related protein and those that make up the virus spike protein are not similar and that spike-targeting antibodies do not cross-react with the implantation protein.

Stress may be responsible for menstrual cycle problems following vaccination.

Some vaccinated women have reported disruptions to their monthly cycle. “We are not dismissing them,” Rosser says. “What they say about their own bodies is important, and they know their bodies best.”

But nothing in the vaccines is a likely candidate to explain these complaints. Experts agree that a probable indirect factor is stress. Getting a new vaccine is itself stressful, Shirazian says, and many kinds of stressors can throw off a menstrual cycle. The physiological effects of these tensions might disrupt pathways that drive menstrual timing.

The good news, Rosser says, is that any menstrual effects appear to be transient. “I’ve talked to enough women in the last eight months, and it seems as though whatever it is, it’s short-lived,” she says.

In early August EMA released a report noting that no cause-and-effect association had been established between complaints of menstrual disruptions and COVID-19 vaccination. Separately, MHRA found no link between menstrual disorders and COVID vaccines.

Some descriptions of menstrual problems mention clotting during heavier periods. Shirazian says that the term “blood clot” as it relates to menstrual flow is different from the term used medically to describe a clot in a blood vessel. “They have nothing to do with each other,” she says. The clotting of menstrual blood happens as the blood exits the vessels and is not a risk for blocking flow to tissues.

COVID-19 may affect the menstrual cycle.

Becoming ill with COVID is associated with clotting in the medical sense—producing pulmonary embolisms that block blood flow to the lungs, for instance. Some evidence also points to the effects of SARS-CoV-2 on menstrual cycles. A small study of 177 patients who had COVID-19, published in September 2020, showed that 28 percent experienced cycle disruptions, including less bleeding and a longer cycle.

Infectious diseases themselves also are a stressor, Rosser says. “Illness causes stress,” she adds. And next to any menstrual cycle disruptions that might follow vaccination, “it’s 100 percent worse to have COVID, if you had to choose between the two,” Shirazian says.

Vaccines do not threaten sperm or erectile function, but COVID-19 does.

Ranjith Ramasamy, director of reproductive urology at the University of Miami, has published several studies describing the novel coronavirus in penile and testicular tissue and its effects on erectile dysfunction. He and his colleagues also looked at the potential effects of vaccines in these areas and found none.

To Ramasamy, the most unsurprising observation was how COVID-19 interferes with erections, which rely on blood flow. “COVID affects the blood vessels that supply organs, and the penis is not much different from other organs that require a lot of blood,” he says.

What was more surprising was the presence of SARS-CoV-2 in penile tissue even nine months after an infection. These results were from a small study of people with penile implants because of severe erectile dysfunction. The rich blood supply to the penis seems to have ensured a route for the virus to these tissues, Ramasamy says.

Like many viruses, SARS-CoV-2 also finds its way into the testes, where it can enter cells and cause damage. A biopsy study of testis tissue from six people who died of COVID-19 showed the virus still lingering in a sample from one of the patients and decreased sperm counts in another three. A sample from a patient who had survived the disease also showed persistent SARS-CoV-2 in the testes.

Ramasamy and his colleagues have found no detrimental changes in sperm counts and other fertility measures after vaccination. “One of the biggest myths with the vaccine was that it could affect fertility,” he says, and finding no negative effect on sperm counts “was very reassuring.”


Some last words on vaccination and the ill effects of COVID-19.

All of the experts had the same take-home message: the key to protecting against the reproductive and sexual effects of COVID-19 is to get vaccinated.

Friday, July 25, 2014

Nexus

Inquiring Minds:
The main focus is on trying to figure out what the real differences are between us politically; and how that knowledge is being used (IMHO) to drive us apart.



But don't forget to take a look at this:



Here's the link to the article in Atmospheric Chemistry and Physics
A team of Greek and German researchers has shown that the colours of sunsets painted by famous artists can be used to estimate pollution levels in the Earth’s past atmosphere. In particular, the paintings reveal that ash and gas released during major volcanic eruptions scatter the different colours of sunlight, making sunsets appear more red. The results are published today in Atmospheric Chemistry and Physics, an open access journal of the European Geosciences Union (EGU).
When the Tambora volcano in Indonesia erupted in 1815, painters in Europe could see the colours of the sky changing. The volcanic ash and gas spewed into the atmosphere travelled the world and, as these aerosol particles scattered sunlight, they produced bright red and orange sunsets in Europe for up to three years after the eruption. J. M. W. Turner was one of the artists who painted the stunning sunsets during that time. Now, scientists are using his, and other great masters’, paintings to retrieve information on the composition of the past atmosphere.
“Nature speaks to the hearts and souls of great artists,” says lead-author Christos Zerefos, a professor of atmospheric physics at the Academy of Athens in Greece. “But we have found that, when colouring sunsets, it is the way their brains perceive greens and reds that contains important environmental information.”

Wednesday, July 16, 2014

What We Choose To Believe

If I project backwards 40 or 50 thousand years, it's not hard to understand how a species capable of rational thought could look at this and make the simplest Type 1 Error by ascribing agency to it.  How do you not when you have no way of knowing otherwise?



Now, as a species capable of rational thought, and knowing what we know, how do we look at this and stop wondering just because we're more comfortable with ignorance and superstition?