Feb 27, 2021

COVID-19 Update

World
New Cases:   432,779 (⬆︎ .38%)
New Deaths:      9,859 (⬆︎ .39%)

USA
New Cases:   80,625 (⬆︎ .28%)
New Deaths:    2,246 (⬆︎ .43%)

Vaccination Scorecard
Total Vaccinations:          47.2 million
Total Priority Population: 38.7%
Total Population:             14.2%




I dunno - first, I just don't think it's likely that I wouldn't recognize most of the people I know - mask or no mask. Add a hat and dark glasses, and it could get a little dicey, but still.

Second, suffering through a few awkward moments doesn't really seem like a huge thing - and if you're having difficulty identifying family members, maybe you should be paying a lot closer attention to them in general.

But, to be more charitable, maybe what's needed is a little perspective, and maybe a little patience (something I should work on my own bad self).


We’re having trouble recognizing each other in masks, and it’s getting awkward

For a few fleeting moments as he sat in a Panera, Todd Hagopian wondered if he’d made a grave mistake.

Hagopian, 40 and a business owner in Bixby, Okla., had just left home on a Wednesday morning in January when a colleague called him about a situation at the office. Rather than waiting to deal with it once he arrived, he pulled his car into the nearest Panera parking lot and grabbed a table inside. As he spoke on the phone in what he described as a loud, “not so happy” voice, a woman peered at him from around the corner.

“I gave her a look like, ‘What are you looking at? I’m in the middle of a work call.’ Then I just gave her a nod,” Hagopian said, “like you’d give to any stranger who you made eye contact with.” The woman walked away to pick up her food, then glanced over again.

As soon as he hung up, the same woman approached Hagopian’s table. She removed her mask and Hagopian found himself face-to-face with Andrea, his wife of 10 years and the mother of his four sons.

She had just said goodbye to him at home an hour earlier. “Did you just nod at me?” she asked him.

In his defense, his wife was not someone Hagopian expected to bump into on this particular morning at this particular Panera. “I’m usually at work by then, and I didn’t know that that was part of her morning routine,” Hagopian said.

He followed his wife out to her car to make sure she wasn’t upset. Much to his relief, she wasn’t; by the time they got in their separate cars, the two were laughing about it. But just to be sure, Hagopian later sent his wife a bouquet. She posted a photo to Facebook with the caption, “Thank you random stranger from Panera Bread for the gorgeous flowers.”

Ever since we were told to wear masks 11 months ago, our social life has been adjusting. When dining out, we’ve learned when to put them on (when the server approaches) and when they can come off (during the eating portion, assuming we want to actually ingest our meals). We’ve learned to nudge, elbow or kick our partners when we want to discreetly grab their attention, rather than silently mouthing words.

But some of us are still having trouble placing a familiar face, winding up in the surreal, often embarrassing predicaments of having failed to recognize colleagues, friends, neighbors and even members of our own family. In the age of social distancing, it certainly hasn’t made anyone feel less alienated from other people.

In Washington, new colleagues within the Biden administration keep awkwardly reintroducing themselves to one another as they try to get acquainted while masked, the New York Times reported. Senate Majority Leader Charles E. Schumer (D-N.Y.) recently ran into Alex Moffat, the actor who plays him on “Saturday Night Live” — and needed a moment to recognize him behind his mask. Meanwhile, Steve Martin has joked that he’s not sure he’s comfortable with so much anonymity, and has begun wearing a sign with his name on it.

Tiffany Graves, a 45-year-old lawyer from Ridgeland, Miss., was out running errands recently when she was greeted by name by a stranger. Graves found herself responding with a wary, noncommittal “Hey.” After a moment, the stranger realized what was happening and pulled down his mask to reveal his face.

“As an attorney, you always want to know your judges,” Graves said. “Not only is he a federal judge, but he’s, like, a good friend. Someone who I really look up to and admire. I was mortified.”

T. Greg Doucette, a criminal defense attorney in Durham, N.C., had his own misadventure in covid-era lawyering when he introduced himself earlier this month to someone he’d just met at the local courthouse. The young man then pointed out that Doucette, 39, had interacted with him on several occasions in a mentorship capacity at his law school before the man graduated in spring 2020.

“I tried to cover it up,” Doucette admitted. “But it was embarrassing. I’ve sat and talked with this guy, and couldn’t recognize him.”

Certainly, these gaffes could happen to anyone who’s proverbially “bad with faces,” even ones without masks. What happened to Clarke Betz, however, is a different story. The 21-year-old shop owner and model from Manhattan Beach, Calif., recently traveled to Washington to visit her long-distance boyfriend. She didn’t tell him what time her flight was getting in, in hopes she could surprise him at the deli where he works. It didn’t go as planned. “I walked past him three times. I said, ‘Hi, Henry,’ but he didn’t hear me because of the mask,” Betz said. Eventually, humiliated, she left.

“I just figured he was really busy,” she said. Later, when he met her at her hotel, Betz asked why he hadn’t acknowledged her. He was aghast: He hadn’t known she was there at all. She has since surprised him at work again — with vastly improved results.

And Megan McDonald, a 34-year-old office manager in Las Vegas, recently made local news headlines with her mask mishap. Last summer, McDonald found out she’d won a raffle for a jersey autographed by one of her favorite hockey players, Marc-Andre Fleury of the Vegas Golden Knights. Months later, on Jan. 18, McDonald was watching television at home, and when the doorbell rang and her Ring camera showed a man in a mask, she figured he was a salesman and ignored it. Fifteen minutes later, she got an email from Fleury’s agent. Fleury had come to deliver the jersey himself. He left it in a Whole Foods bag on her doorstep.

“I was like, ‘Wow, does he think I’m a total jerk?’ Because he probably heard someone there,” McDonald recalled. “Hopefully one day I’ll run into him and be like, ‘Hey, remember that time …? Sorry about that.’ ”

Caroline Blais, a psychology professor at Canada’s University of Quebec in Outaouais who has done studies on facial processing, said that humans’ ability to recognize each other varies widely. Some may only need 10 percent of the face — one eye, maybe even just an eyebrow — to be able to place someone. It’s generally easier for people to recognize faces by just the top half than just the bottom half.

“For most people, the eye area provides a lot of information about identity,” she said.

There are ways to fight the nuisance of Involuntary Mask Anonymity. Wear a mask that reveals your company, or your favorite sports team, or your name, like the one Rep. Robin L. Kelly (D-Ill.) recently wore on Capitol Hill. Or one of those screen-printed masks emblazoned with the bottom half of your face (though as Blais admitted, those are “a bit creepy”).

That said, some of us love the anonymity that masks provide — and the plausible deniability of “not recognizing” someone else. Graves is sometimes quietly thrilled to slip past a too-friendly acquaintance in the grocery store. “There are those times when people does recognize you and they want to be really chatty,” she said. Sometimes they take their masks down to be heard more easily and beckon her to take hers off, too. “I’m like, ‘No! I’m in public. I’m not trying to stand around and do this right now!’ ”

But for others, obscured faces are a recurrent source of agitation. Hagopian, the Oklahoman who failed to recognize his wife at Panera, acknowledges that he’s among the many who suffer from mask-induced face blindness. Local food trucks sometimes visit his neighborhood, and when he bumps into a neighbor waiting in line, what would otherwise be a pleasantly surprising encounter often turns into a panicked one. No neighbor has trouble recognizing Hagopian, who’s short and has a distinctive voice. But from his point of view, “Everyone’s 5-9 and White,” he said with a laugh.

The loss of the ability to immediately recognize friends and acquaintances is one of the more minor “tiny violin” tragedies of the coronavirus pandemic. But it can add an extra bit of stress and loneliness to an already stressful, lonely year. “We’re obviously not having as many conversations with people out in the open as we normally would in those types of situations — or any meaningful conversations,” Hagopian said. It’s just one more reason he wants the pandemic to end: “I would say the sooner we can get back to normal, probably, the better.”

Today's Pix

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Feb 26, 2021

Vroom Zoom Kaboom

Fill 'er up - and I'm gonna need a little coffee - and maybe some Advil or something?

Lady Day

Real, soul-crushing tragedy was part of Billie Holiday's life, and some would certainly hypothesize that it's what really drives anyone who inhabits The Blues the way a Billie Holiday could.

But that drama doesn't have to be a defining thing. For humans, it can be a strong colorative aspect, and have a deep important influence, but it almost never actually defines the person completely.

We're just kind of amazing that way.







COVID-19 Update

World
New Cases:   449,697 (⬆︎ .40%)
New Deaths:    10,578 (⬆︎ .42%)

USA
New Cases:   77,377 (⬆︎ .27%)
New Deaths:    2,414 (⬆︎ .47%)

Vaccination Scorecard
Total Vaccinations:          46.1 million
Total Priority Population: 37.8%
Total Population:             13.9%




People keep telling me the monster is receding, but there are troubling signs, even though optimism is still in order.

And that's kinda the maddening aspect of it - there's reason to be optimistic, but that has to be kept in the context of knowing there are so many fucking idiots out there pimping bullshit and refusing to do the simplest little thing to help themselves, let alone everybody else in the process.

CPAC comes to mind:


NYT: (pay wall)

The Coronavirus Is Plotting a Comeback. Here’s Our Chance to Stop It for Good.

Across the United States, and the world, the coronavirus seems to be loosening its stranglehold. The deadly curve of cases, hospitalizations and deaths has yo-yoed before, but never has it plunged so steeply and so fast.

Is this it, then? Is this the beginning of the end? After a year of being pummeled by grim statistics and scolded for wanting human contact, many Americans feel a long-promised deliverance is at hand.

Americans will win against the virus and regain many aspects of their pre-pandemic lives, most scientists now believe. Of the 21 interviewed for this article, all were optimistic that the worst of the pandemic is past. This summer, they said, life may begin to seem normal again.

But — of course, there’s always a but — researchers are also worried that Americans, so close to the finish line, may once again underestimate the virus.

So far, the two vaccines authorized in the United States are spectacularly effective, and after a slow start, the vaccination rollout is picking up momentum. A third vaccine is likely to be authorized shortly, adding to the nation’s supply.

But it will be many weeks before vaccinations make a dent in the pandemic. And now the virus is shape-shifting faster than expected, evolving into variants that may partly sidestep the immune system.

The latest variant was discovered in New York City only this week, and another worrisome version is spreading at a rapid pace through California. Scientists say a contagious variant first discovered in Britain will become the dominant form of the virus in the United States by the end of March.

The road back to normalcy is potholed with unknowns: how well vaccines prevent further spread of the virus; whether emerging variants remain susceptible enough to the vaccines; and how quickly the world is immunized, so as to halt further evolution of the virus.

But the greatest ambiguity is human behavior. Can Americans desperate for normalcy keep wearing masks and distancing themselves from family and friends? How much longer can communities keep businesses, offices and schools closed?

Covid-19 deaths will most likely never rise quite as precipitously as in the past, and the worst may be behind us. But if Americans let down their guard too soon — many states are already lifting restrictions — and if the variants spread in the United States as they have elsewhere, another spike in cases may well arrive in the coming weeks.

Scientists call it the fourth wave. The new variants mean “we’re essentially facing a pandemic within a pandemic,” said Adam Kucharski, an epidemiologist at the London School of Hygiene and Tropical Medicine.The declines are real, but they disguise worrying trends.


The United States has now recorded 500,000 deaths amid the pandemic, a terrible milestone. As of Wednesday morning, at least 28.3 million people have been infected.

But the rate of new infections has tumbled by 35 percent over the past two weeks, according to a database maintained by The New York Times. Hospitalizations are down 31 percent, and deaths have fallen by 16 percent.

Yet the numbers are still at the horrific highs of November, scientists noted. At least 3,210 people died of Covid-19 on Wednesday alone. And there is no guarantee that these rates will continue to decrease.

“Very, very high case numbers are not a good thing, even if the trend is downward,” said Marc Lipsitch, an epidemiologist at the Harvard T.H. Chan School of Public Health in Boston. “Taking the first hint of a downward trend as a reason to reopen is how you get to even higher numbers.”

In late November, for example, Gov. Gina Raimondo of Rhode Island limited social gatherings and some commercial activities in the state. Eight days later, cases began to decline. The trend reversed eight days after the state’s pause lifted on Dec. 20.

The virus’s latest retreat in Rhode Island and most other states, experts said, results from a combination of factors: growing numbers of people with immunity to the virus, either from having been infected or from vaccination; changes in behavior in response to the surges of a few weeks ago; and a dash of seasonality — the effect of temperature and humidity on the survival of the virus.

Parts of the country that experienced huge surges in infection, like Montana and Iowa, may be closer to herd immunity than other regions. But patchwork immunity alone cannot explain the declines throughout much of the world.

The vaccines were first rolled out to residents of nursing homes and to the elderly, who are at highest risk of severe illness and death. That may explain some of the current decline in hospitalizations and deaths.

But young people drive the spread of the virus, and most of them have not yet been inoculated. And the bulk of the world’s vaccine supply has been bought up by wealthy nations, which have amassed one billion more doses than needed to immunize their populations.


Vaccination cannot explain why cases are dropping even in countries where few have been immunized. The biggest contributor to the sharp decline in infections is something more mundane, scientists say: behavioral change.

Leaders in the United States and elsewhere stepped up community restrictions after the holiday peaks. But individual choices have also been important, said Lindsay Wiley, an expert in public health law and ethics at American University in Washington.

“People voluntarily change their behavior as they see their local hospital get hit hard, as they hear about outbreaks in their area,” she said. “If that’s the reason that things are improving, then that’s something that can reverse pretty quickly, too.”

The downward curve of infections with the original coronavirus disguises an exponential rise in infections with B.1.1.7, the variant first identified in Britain, according to many researchers.

“We really are seeing two epidemic curves,” said Ashleigh Tuite, an infectious disease modeler at the University of Toronto.

The B.1.1.7 variant is thought to be more contagious and more deadly, and it is expected to become the predominant form of the virus in the United States by late March. The number of cases with the variant in the United States has risen from 76 in 12 states as of Jan. 13 to more than 1,800 in 45 states now. Actual infections may be much higher because of inadequate surveillance efforts in the United States.

Buoyed by the shrinking rates over all, however, governors are lifting restrictions across the United States and are under enormous pressure to reopen completely. Should that occur, B.1.1.7 and the other variants are likely to explode.

“Everybody is tired, and everybody wants things to open up again,” Dr. Tuite said. “Bending to political pressure right now, when things are really headed in the right direction, is going to end up costing us in the long term.”
Another wave may be coming, but it can be minimized.

Looking ahead to late March or April, the majority of scientists interviewed by The Times predicted a fourth wave of infections. But they stressed that it is not an inevitable surge, if government officials and individuals maintain precautions for a few more weeks.

A minority of experts were more sanguine, saying they expected powerful vaccines and an expanding rollout to stop the virus. And a few took the middle road.

“We’re at that crossroads, where it could go well or it could go badly,” said Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases.

The vaccines have proved to be more effective than anyone could have hoped, so far preventing serious illness and death in nearly all recipients. At present, about 1.4 million Americans are vaccinated each day. More than 45 million Americans have received at least one dose.

A team of researchers at Fred Hutchinson Cancer Research Center in Seattle tried to calculate the number of vaccinations required per day to avoid a fourth wave. In a model completed before the variants surfaced, the scientists estimated that vaccinating just one million Americans a day would limit the magnitude of the fourth wave.

“But the new variants completely changed that,” said Dr. Joshua T. Schiffer, an infectious disease specialist who led the study. “It’s just very challenging scientifically — the ground is shifting very, very quickly.”

Natalie Dean, a biostatistician at the University of Florida, described herself as “a little more optimistic” than many other researchers. “We would be silly to undersell the vaccines,” she said, noting that they are effective against the fast-spreading B.1.1.7 variant.

But Dr. Dean worried about the forms of the virus detected in South Africa and Brazil that seem less vulnerable to the vaccines made by Pfizer and Moderna. (On Wednesday, Johnson & Johnson reported that its vaccine was relatively effective against the variant found in South Africa.)

About 50 infections with those two variants have been identified in the United States, but that could change. Because of the variants, scientists do not know how many people who were infected and had recovered are now vulnerable to reinfection.

South Africa and Brazil have reported reinfections with the new variants among people who had recovered from infections with the original version of the virus.

“That makes it a lot harder to say, ‘If we were to get to this level of vaccinations, we’d probably be OK,’” said Sarah Cobey, an evolutionary biologist at the University of Chicago.

Yet the biggest unknown is human behavior, experts said. The sharp drop in cases now may lead to complacency about masks and distancing, and to a wholesale lifting of restrictions on indoor dining, sporting events and more. Or … not.

“The single biggest lesson I’ve learned during the pandemic is that epidemiological modeling struggles with prediction, because so much of it depends on human behavioral factors,” said Carl Bergstrom, a biologist at the University of Washington in Seattle.

Taking into account the counterbalancing rises in both vaccinations and variants, along with the high likelihood that people will stop taking precautions, a fourth wave is highly likely this spring, the majority of experts told The Times.

Kristian Andersen, a virologist at the Scripps Research Institute in San Diego, said he was confident that the number of cases will continue to decline, then plateau in about a month. After mid-March, the curve in new cases will swing upward again.

In early to mid-April, “we’re going to start seeing hospitalizations go up,” he said. “It’s just a question of how much.”
Summer will feel like summer again, sort of.

Now the good news.

Despite the uncertainties, the experts predict that the last surge will subside in the United States sometime in the early summer. If the Biden administration can keep its promise to immunize every American adult by the end of the summer, the variants should be no match for the vaccines.

Combine vaccination with natural immunity and the human tendency to head outdoors as weather warms, and “it may not be exactly herd immunity, but maybe it’s sufficient to prevent any large outbreaks,” said Youyang Gu, an independent data scientist, who created some of the most prescient models of the pandemic.

Infections will continue to drop. More important, hospitalizations and deaths will fall to negligible levels — enough, hopefully, to reopen the country.

“Sometimes people lose vision of the fact that vaccines prevent hospitalization and death, which is really actually what most people care about,” said Stefan Baral, an epidemiologist at the Johns Hopkins Bloomberg School of Public Health.

Even as the virus begins its swoon, people may still need to wear masks in public places and maintain social distance, because a significant percent of the population — including children — will not be immunized.

“Assuming that we keep a close eye on things in the summer and don’t go crazy, I think that we could look forward to a summer that is looking more normal, but hopefully in a way that is more carefully monitored than last summer,” said Emma Hodcroft, a molecular epidemiologist at the University of Bern in Switzerland.

Imagine: Groups of vaccinated people will be able to get together for barbecues and play dates, without fear of infecting one another. Beaches, parks and playgrounds will be full of mask-free people. Indoor dining will return, along with movie theaters, bowling alleys and shopping malls — although they may still require masks.

The virus will still be circulating, but the extent will depend in part on how well vaccines prevent not just illness and death, but also transmission. The data on whether vaccines stop the spread of the disease are encouraging, but immunization is unlikely to block transmission entirely.

“It’s not zero and it’s not 100 — exactly where that number is will be important,” said Shweta Bansal, an infectious disease modeler at Georgetown University. “It needs to be pretty darn high for us to be able to get away with vaccinating anything below 100 percent of the population, so that’s definitely something we’re watching.”

Over the long term — say, a year from now, when all the adults and children in the United States who want a vaccine have received them — will this virus finally be behind us?

Every expert interviewed by The Times said no. Even after the vast majority of the American population has been immunized, the virus will continue to pop up in clusters, taking advantage of pockets of vulnerability. Years from now, the coronavirus may be an annoyance, circulating at low levels, causing modest colds.

Many scientists said their greatest worry post-pandemic was that new variants may turn out to be significantly less susceptible to the vaccines. Billions of people worldwide will remain unprotected, and each infection gives the virus new opportunities to mutate.

“We won’t have useless vaccines. We might have slightly less good vaccines than we have at the moment,” said Andrew Read, an evolutionary microbiologist at Penn State University. “That’s not the end of the world, because we have really good vaccines right now.”

For now, every one of us can help by continuing to be careful for just a few more months, until the curve permanently flattens.

“Just hang in there a little bit longer,” Dr. Tuite said. “There’s a lot of optimism and hope, but I think we need to be prepared for the fact that the next several months are likely to continue to be difficult.”

Today's Tweet



So this is a little scary


On Brand Loyalty

Let me just get this one out real quick.

I think Andrew Cuomo did a pretty good job under ridiculously shitty circumstances last year.

And while, apparently, he wasn't always as straight up and honest about everything as he should've been, at least he was a calming voice, reassuring people that there was a huge effort going on that had some of the best professionals in the world working the problem. Which is a valuable thing, especially considering what a total FUBAR Qult45 was making of it.

That said, if it turns out Cuomo pulled some real shit, and this scandal really is a scandal - not just something cooked up by his rivals and his enemies - then he should burn.

I'm almost always with the Dems these days, but I'm not so stoopid as to stick with a guy who turns out to be a typically cynical manipulator just because they put a (D) after his name - I don't care what it says on his label, if he pulled some crooked shit, then let that shit land on his head.


WaPo: (pay wall)

Andrew Cuomo, once touted as the ‘gold standard,’ finds his brand tarnished by multiple crises

As the coronavirus pandemic ravaged the country last year, New York Gov. Andrew M. Cuomo launched an Emmy-winning daytime television show, using his daily briefings to channel the nation’s grief, showcase how he was taking charge and share the secrets of his family’s spaghetti dinners. He published a best-selling book about his leadership, saw his state approval numbers rise to 66 percent and repeatedly denied any interest in the next logical step: running for president.

Now, cases of covid-19 in his state are receding, and so are the glory days of Cuomo’s third term as governor.

A former adviser has accused him of sexual harassment, fellow Democrats are publicly condemning what they describe as bullying backroom behavior, and federal investigators are probing the state’s handling of nursing home data amid allegations that Cuomo’s administration withheld the extent of deaths caused by the virus.

The sudden shift in fortunes for Cuomo, which has potentially clouded what looked to be an easy reelection campaign next year, comes as an abrupt turnabout for those who first encountered the governor during his daily news conferences. He was widely praised for offering the country the sort of strong leadership many saw missing from the White House under President Donald Trump. The International Academy of Television Arts & Sciences gave him an Emmy for “his masterful use of television to inform and calm people around the world.” He even welcomed the term “Cuomosexual” used by some of his online fans.

But for those steeped in New York politics, little is surprising about the recent turn of events, save perhaps how many people have publicly turned against the governor. The rough edges Cuomo once sold as an asset — “My natural instinct is to be aggressive,” he wrote in his last book — are now emerging as a liability.

“This is not just an aggressive politician. This is someone who has a narrative, and if you do not publicly agree with that narrative, he will threaten you,” said Monica Klein, a liberal activist who previously worked for New York Mayor Bill de Blasio (D), a fierce rival of the governor. “What that means is dissent is silenced.”

Aides to Cuomo have denied the sexual harassment allegation and defended his administration’s handling of nursing home data.

“New Yorkers know it was the Governor who worked night and day to get them through the worst of this pandemic and, from the strongest gun safety laws in the nation to a $15 minimum wage and free college tuition, he has a nationally significant record of progressive accomplishments that Washington is trying to match,” Rich Azzopardi, a senior adviser to Cuomo, said in a statement.

But public dissent is now spreading through New York political circles — and notably within Cuomo’s own party — as a growing number of rising politicians calculate that they can succeed without the help of the governor’s machine. Assemblyman Ron Kim (D) of Queens, who has been critical of Cuomo’s handling of nursing home data, said the governor threatened to “destroy” him earlier this month if he did not retract his comments.

Cuomo’s advisers denied Kim’s description of the call, and Cuomo attacked the lawmaker personally, suggesting at a news conference that Kim had improperly raised money from small businesses in his district whose legislative priorities he supported.


The piece goes on to recount several he-said-she-said exchanges, but the gist remains that this is most probably a new telling of the same old political story of (Talent + Success) x Adulation = Hubris and Misstep and Downfall.

The Downfall part remains to be seen, but the bloom is definitely off the rose.

Feb 25, 2021

Today's Video

Wild animals are not to be fucked with - they are to be respected and admired from a distance.

But damn - it's hard to resist the urge to just wade right in.


Let's be careful out there.

It's Not The Irony, Stupid


It's something we don't get to know about - or maybe it really is just as plain as the warts on Joe Manchin's dick.


Opinion: What terrible things did Neera Tanden tweet? The truth.

Can you believe that Neera Tanden called Hillary Clinton the “anti-Christ” and the “real enemy”?

Oh, wait. It was Ryan Zinke who said those things. Fifty-one Republican senators (and several Democrats, including Joe Manchin III of West Virginia) confirmed him as secretary of the interior in 2017.

And how about the times Tanden allegedly called the NAACP a “pinko organization” that “hates white people” and used racial epithets?

My bad. That was Jeff Sessions. Again, 51 Republican senators (and one Democrat, Manchin) voted to confirm him as attorney general in 2017.

Surely Tanden went beyond the pale when she “liked” a tweet calling then-Secretary of State John F. Kerry a “traitor” and “Vietnam’s worst export,” and when she suggested Clinton supporters leave the country.

Except Mike Pompeo was the one who did those things. He won confirmation as secretary of state in 2018 with the votes of 50 Republicans and six Democrats, including Manchin.

But, really, the most appalling thing Tanden said was that Muslims have a “deficient theology” and they “stand condemned.”

Whoops. That wasn’t Tanden but Russell Vought. Just last year, 51 Republicans voted to confirm him as director of the Office of Management and Budget — the same position Tanden is up for now.

Now, all 50 Senate Republicans, assisted by Manchin, are on the cusp of sinking Tanden’s nomination because they object to her harsh tweets. Many have noted the hypocrisy, particularly when compared with the treatment of Richard Grenell, an online troll who won confirmation as ambassador to Germany with 50 Republican votes — and Manchin, natch — despite routinely disparaging women’s appearances.

But this isn’t just about double standards. What really must sting about Tanden’s tweets is not that they were mean, but that, for the most part, they were true.

In June 2019, she lashed out at then-Senate Majority Leader Mitch McConnell for blocking bipartisan attempts to protect U.S. elections from foreign attack. “Can people on here please focus their ire on McConnell and the GOP senators who are Up This Cycle who enable him?” she asked in one deleted tweet.

Such pressure eventually forced McConnell to allow for more funds for election security.

Another deleted tweet charged: “Apparently a lot of people think #MoscowMitch is a threat.”

A lot of people did. I wrote that his determination to thwart bipartisan election protections made him a “Russian asset.”

After then-President Donald Trump called former aide Omarosa Manigault Newman a “crazed, lying lowlife” and a “dog,” Tanden’s now-deleted tweet said: “Trump just called a black woman a dog and about 80% of the GOP don’t think he’s racist. The whole party needs to be defeated in November.”

Couldn’t have said it better myself.

After Trump endorsed Senate candidate Roy Moore in Alabama and the Republican National Committee poured money into supporting Moore, accused by several women of sexually assaulting them as teenagers, Tanden’s now-deleted tweet responded: “The Republican party is gleefully supporting an alleged child molester. And everyone who gives money to the RNC is doing the same.”

Tough but fair.

She made a tactical mistake calling Sen. Susan Collins (R-Maine) “the worst” for taking Brett M. Kavanaugh’s word over his sexual-assault accuser’s, calling the theatrically dour Sen. Tom Cotton (R-Ark.) a “fraud” and saying Sen. Ted Cruz (R-Cancún) is as heartless as a “vampire.” (But if the shoe fits . . .)

Tanden, unlike most of the Trump nominees, apologized for her tone and promised that her words as a public official would be different. She explained that “the last several years have been very polarizing.”

I feel the same way. I wince at some of the caustic and ad hominem things I wrote during the Trump era. Trump made almost all of us angrier.

Trump abandoned norms of democracy and decency and stoked racial hatred and violence. But equally infuriating was that elected Republican officials did almost nothing to stop him. In the end, 147 Republicans voted to overturn the election results, even after the bloody insurrection in the Capitol, and 43 Senate Republicans just voted to acquit Trump.

We all want healing. We all want unity. But it won’t happen as long as the Party of Trump assigns Democrats sole responsibility for civility, while using President Biden’s admirable talk of unity as a cudgel. Collins moralized about Tanden representing “the kind of animosity that President Biden has pledged to transcend.” In other words, apology not accepted.

And it’s not just Tanden. Senate Republicans this week teed off on Biden’s interior secretary nominee, Deb Haaland, another woman of color, over her 2020 tweet saying that “Republicans don’t believe in science.” Sen. John Barrasso (R-Wyo.), who has cast doubt on the human role in climate change, called the tweet “concerning.”


No, senator. What’s “concerning” is that, after four years of excusing lies, racism, vulgarity, lawbreaking and self-dealing by the Trump administration, your idea of healing is to defeat Biden nominees for speaking the truth.

COVID-19 Update

World
New Cases:   438,560 (⬆︎ .39%)
New Deaths:    10,886 (⬆︎ .44%)

USA
New Cases:   75,299 (⬆︎ .26%)
New Deaths:    2,525 (⬆︎ .49%)

Vaccination Scorecard
Total Vaccinations:          45.2 million
Total Priority Population: 37.1%
Total Population:             13.6%




As the ramp-up continues, the race is on - and for some, of course, it won't be about who can make the most vaccine, but who can make the best bank.

A big problem requires a big response, which requires a big dollar outlay, which provides big opportunity for the Rent-Seekers and Short-Run Sharks to suck around for the easy money.

I'm being a little cynical, but there's always the potential for abuse, even as we raise the prospects for something good to come of a bad situation.


Wanted: More high-tech manufacturing space for a global vaccine push

The number of available COVID-19 vaccine doses is steadily rising, but a shortage of physical space that meets standards for pharmaceutical manufacturing is a major bottleneck to further expansion, according to drugmakers, industry construction experts and officials involved in the U.S. vaccine program.

The production of raw materials, vaccine formulation and vial filling all require “clean rooms” with features like air cleaners, sterile water and sterilizing steam designed and in some cases built by specialists.

Moderna Inc on Wednesday announced plans to expand vaccine manufacturing capacity, but said it will be a year before that can add to its production.

With vaccines needed for billions of people to end a pandemic that has claimed more than 2.5 million lives globally, drugmakers have even had to turn to rivals for help to churn out doses. Space at third-party contract manufacturers in the United States is largely allocated, according to one major contract manufacturer and other smaller companies.

A recent U.S. Government Accountability Office report flagged a shortage of manufacturing capacity as a challenge in scaling up vaccine production.

And the emergence of new coronavirus variants is likely to increase the strain on production capacity.

Public health experts say global vaccination as soon as possible is critical to curbing the rise of highly contagious additional variants. Many are counting on authorization of Johnson & Johnson’s vaccine this week.

Longer term, tackling COVID-19 may require annual shots to protect against new virus mutations, similar to the flu. Vaccine companies are already designing potential booster shots addressing variants first identified in South Africa and Brazil.

“What’s happening now indicates the importance of markedly strengthening the capacity of manufacturing capabilities in the United States,” said Larry Corey, a virologist at the Fred Hutchinson Cancer Research Center who helped design U.S.-backed vaccine trials. “We should be investing, large scale, in our abilities to manufacture.”

Pfizer and Moderna can increase output some by speeding fill and finish, said Moncef Slaoui, former chief scientific adviser for the government’s Operation Warp Speed vaccine program. Making much more vaccine itself is more challenging.

“To change that substantially in terms of drug substance would take ramping up global manufacturing infrastructure. That takes months,” he said. “You would have to build, train, validate, and get regulators to visit and approve a site.”

Leading vaccine developers Pfizer and partner BioNTech, Moderna, AstraZeneca, J&J, Novavax, Russia’s Gamaleya Research Institute, and CureVac are aiming to make enough vaccine with manufacturing partners to inoculate some 5.2 billion people in 2021, according to a Reuters tally of public statements and media reports.

China’s Sinovac and Sinopharm will likely deliver significant supplies as well, though their 2021 targets are unclear. Several drugmakers have struggled to meet early production targets.
BUILDING FASTER

Building new facilities and even expanding existing manufacturing sites has typically taken years. During the pandemic, some projects have been completed in as little as 6-to-10 months, according to some specialized construction companies involved with Warp Speed.

Emergent BioSolutions , which is making J&J and AstraZeneca vaccines for the United States, cannot add any more equipment to facilities dedicated to those vaccines.

The company is not alone. “The contract manufacturing network, like our facility, is pretty full,” said Emergent Executive Vice President Sean Kirk.

Adding new clean rooms that meet good manufacturing practices standards is complex and time consuming, said Phil DeSantis, a consultant and pharmaceutical engineer.

“Building the clean room is probably what we call the critical path,” he said. “That’s the part that takes the longest.”

Vaccine makers have sidestepped this in part by retrofitting existing facilities. BioNTech bought a facility in Marburg, Germany, from Novartis in September, and began producing messenger RNA - the active ingredient in its vaccine - in early February.

When Emergent joined Warp Speed last year, it stopped everything else it was working on at its Baltimore facility to make room for the COVID-19 vaccines.

The U.S. government can use the Defense Production Act to force that kind of reshuffling. Supply orders with a federal “rating” under the law must be filled first. But there are limits to what it can do without threatening supplies of other injectable medicines.

Pfizer last week said it had engaged two U.S. contract manufacturers and would add capacity to formulate vaccines and make raw materials at its own sites, but did not specify whether new clean rooms would be installed.

In adding clean room space to existing sites, drugmakers and their suppliers have leaned heavily on pre-fabricated wall panels and pods that speed the process, according to specialist companies that build those spaces.

G-CON Manufacturing provided pods to some Warp Speed projects. One contract manufacturer dedicated space to COVID-19 vaccines, and then used G-CON pods to add clean room space for a different project for an existing customer, said Chief Executive Maik Jornitz.

“It was sort of the only way,” Peter Walters, director of advanced therapies at CRB, which designs and manages construction of the facilities, said of the pre-fabricated systems.

CRB has worked on more than 20 coronavirus vaccine-related projects. The program has “certainly redefined, to a lot of the industry, what could be possible,” Walters said.

Adding more capacity would help the United States tackle COVID-19 variants and future pandemics, said Prashant Yadav, a senior fellow at the U.S.-based Center for Global Development.

“We can use it for our own needs,” he said. “We can use it to serve the world.”